Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Protein supplementation is scientifically validated as an important component in the treatment of anorexia, particularly Anorexia Nervosa. Individuals with anorexia often experience severe malnutrition, muscle wasting, and loss of lean body mass due to prolonged caloric and nutrient restriction. Restoring weight and reversing the catabolic state are central goals in the medical management of anorexia. Protein is essential for the repair and rebuilding of tissues, preservation of muscle mass, and immunological support during the refeeding process.

Clinical guidelines, such as those from the National Institute for Health and Care Excellence (NICE) and the American Psychiatric Association (APA), recommend a balanced diet that includes adequate protein intake as part of a comprehensive nutrition rehabilitation plan. Studies have shown that sufficient protein intake during refeeding helps prevent refeeding syndrome, a potentially fatal shift in fluids and electrolytes, and supports the restoration of organ function. Additionally, adequate dietary protein is necessary to promote positive nitrogen balance, which is critical for recovery from the protein-energy malnutrition typical in anorexia.

While protein alone is not a cure for anorexia—psychological and behavioral interventions are essential—scientific evidence supports its use as a crucial part of nutritional rehabilitation. The strength of evidence is high (rated 4/5) due to multiple clinical studies and expert guidelines, though further research into optimal macronutrient composition is ongoing.

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