Evidence supporting the use of: Southern Prickly Ash
For the health condition: Angina

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Southern Prickly Ash (Zanthoxylum clava-herculis) has a history of use in traditional medicine, particularly in North America, where various indigenous groups and early herbalists employed the bark and berries for circulatory complaints, including angina (chest pain related to heart disease). The rationale was based on observed effects such as increased salivation, tingling sensations, and purported stimulant properties, which were believed to enhance blood flow and support cardiovascular function. Early Eclectic physicians in the 19th century recommended Southern Prickly Ash as a circulatory stimulant and tonic, sometimes employing it for ailments like angina pectoris. However, the evidence is primarily anecdotal and based on empirical tradition rather than controlled scientific evaluation.

Modern scientific studies specifically examining the efficacy or mechanism of Southern Prickly Ash for angina are lacking. No high-quality clinical trials or robust pharmacological investigations substantiate its use for this condition. While some phytochemicals in the plant have vasodilatory or anti-inflammatory properties in laboratory settings, these findings do not directly translate to evidence for treating angina in humans. Therefore, its use for angina is rooted in tradition, with only minimal supporting evidence and no scientific validation.

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