Evidence supporting the use of: Safflower
For the health condition: Angina

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Safflower (Carthamus tinctorius) has a long history of use in traditional Chinese medicine, where its dried flowers are known as "Hong Hua." In traditional practice, safflower is used to "invigorate blood" and "dispel blood stasis," which are thought to underlie conditions such as angina (chest pain due to restricted blood flow to the heart). Decoctions and extracts of safflower are often included in herbal formulas for cardiovascular complaints, including angina pectoris, with a belief in their ability to improve circulation and alleviate pain.

While there are some preclinical and small clinical studies suggesting that safflower extracts may have vasodilatory, anti-thrombotic, and anti-inflammatory effects, robust scientific evidence from large, well-designed clinical trials is lacking. The clinical studies that do exist are often of low methodological quality, with small sample sizes and sometimes lack of blinding or randomization. Thus, safflower continues to be used primarily on the basis of tradition rather than strong scientific validation. Modern reviews and pharmacopoeias typically recognize its traditional use for cardiovascular conditions but emphasize the need for further research to confirm both efficacy and safety.

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Products containing Safflower

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