Evidence supporting the use of: L-taurine
For the health condition: Angina

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-taurine has some scientific support for its potential use in the management of angina, although the evidence is still limited and not robust. Taurine is a sulfur-containing amino acid found abundantly in the heart and has been studied for its cardioprotective effects. Preclinical studies suggest that taurine may improve endothelial function, reduce oxidative stress, and stabilize cell membranes. These effects could theoretically benefit individuals with angina by improving blood flow and reducing myocardial oxygen demand.

A small number of clinical studies have examined taurine supplementation in patients with cardiovascular disease. Some trials have reported that taurine may improve exercise capacity and reduce symptoms in patients with heart failure or ischemic heart disease, potentially through mechanisms such as improving calcium handling in cardiac muscle and reducing blood pressure. However, direct evidence specifically targeting angina pectoris is sparse. A few older studies and case reports suggest that taurine supplementation may reduce the frequency and severity of angina attacks, but these studies typically have small sample sizes, lack rigorous controls, or are dated.

In summary, while there is a plausible biological rationale and some early scientific evidence supporting taurine’s use for angina, high-quality, large-scale clinical trials are lacking. Current evidence does not justify its routine use for angina management, but it remains an area of interest for future research.

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