Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B2, also known as riboflavin, has a scientifically validated role in the support and treatment of certain types of anemia, particularly those related to riboflavin deficiency. Riboflavin is essential for normal cellular function and is involved in the metabolism of iron and the synthesis of red blood cells. Deficiency of riboflavin can lead to normocytic, normochromic anemia, and sometimes megaloblastic anemia, as shown in clinical and observational studies. Supplementation with riboflavin has been demonstrated to correct anemia in these deficiency cases, especially in populations with poor dietary intake or malabsorption syndromes. For example, studies have shown that riboflavin supplementation in deficient individuals can improve hemoglobin levels and red blood cell indices. However, riboflavin is not effective for all forms of anemia; it is specifically beneficial when anemia is directly caused by riboflavin deficiency or when it is used as part of a broader strategy to address multiple micronutrient deficiencies. There is insufficient evidence to support the use of riboflavin for anemia unrelated to its deficiency. Therefore, while there is moderate scientific evidence (rated 3/5) supporting its use for riboflavin-deficiency anemia, its efficacy for other forms of anemia is limited and not broadly recommended.

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