Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rubia cordifolia (commonly known as Indian Madder or Manjistha) has a long history of use in traditional Ayurvedic and Unani medicine. In these systems, it is considered a "blood purifier" and is traditionally used to support the treatment of various blood-related disorders, including anemia. The rationale is based on its supposed ability to improve blood quality, remove toxins, and stimulate blood formation. There are references in classical Ayurvedic texts such as the Charaka Samhita and Sushruta Samhita, where Manjistha is recommended for improving complexion and managing diseases associated with "impure blood." However, the modern scientific evidence supporting its effectiveness for anemia specifically is limited and preliminary. Some in vitro and animal studies have suggested that Rubia cordifolia may have hematopoietic (blood-forming) properties, possibly due to its antioxidant constituents and potential to stimulate erythropoiesis, but well-designed human clinical trials are lacking. The herb does contain iron, but not in quantities sufficient to directly treat iron-deficiency anemia. Thus, its primary use for anemia is rooted in tradition rather than strong scientific validation. Current evidence rating is low (2 out of 5), reflecting primarily traditional support with limited scientific exploration and no robust clinical data.

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