Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Helicteres isora, commonly known as the Indian screw tree, has been traditionally used in various systems of medicine, including Ayurveda and folk medicine, for the treatment of anemia. Ethnobotanical surveys and traditional knowledge sources cite its use for improving blood health and treating conditions related to low hemoglobin, likely due to its perceived nutritive and tonic properties. Some traditional preparations involve using the root or fruit as a decoction or powder, administered to individuals showing signs of anemia or general debility.

However, scientific validation for its anti-anemic effect is limited. Only a few in vivo animal studies have explored its hematinic potential, some indicating an increase in hemoglobin and red blood cell counts in experimentally induced anemia in rats, likely due to the presence of polyphenols, flavonoids, and micronutrients in the plant. Nevertheless, these results are preliminary and have not been widely replicated or confirmed in human studies. No robust clinical trials exist to substantiate its efficacy in human anemia, and mechanistic understanding remains speculative. Therefore, while Helicteres isora is indeed traditionally used for anemia, the scientific evidence supporting this claim remains weak and primarily preclinical.

In summary, the use of Helicteres isora for anemia is justified by traditional practices, but current scientific evidence is inadequate for strong recommendations.

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