Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ghee, or clarified butter, is used in Ayurvedic and traditional Indian medicine as part of the management of anal fistula and fissure. Its use is primarily traditional, based on the text and practice of Ayurveda. In this context, ghee is applied topically or used as a base for medicated formulations (such as jatyadi ghrita) that are introduced into the anal canal to promote wound healing, reduce inflammation, and provide lubrication, which may ease pain during defecation. Classical Ayurvedic texts like the Sushruta Samhita recommend ghee for its supposed vrana ropana (wound healing) properties.

However, direct scientific evidence supporting the efficacy of ghee in treating anal fistula or fissure is minimal. Most available studies are small, not rigorously controlled, and often combine ghee with herbal ingredients, making it difficult to isolate its effects. The rationale for its use is based more on traditional belief and empirical use rather than robust clinical trials. Some experimental data suggest ghee may have mild anti-inflammatory and antimicrobial properties, but these findings have not been translated into high-quality clinical evidence for anal fistula or fissure.

In summary, while ghee is traditionally used in Ayurvedic management of these conditions, scientific validation is limited and the evidence base remains weak.

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