Evidence supporting the use of: Walnut (unspecified)
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

There is some scientific evidence suggesting that walnut (Juglans spp.) consumption may have beneficial effects relevant to Alzheimer's Disease (AD), but the evidence is preliminary and mostly based on animal studies and limited human data. Walnuts are rich in polyunsaturated fatty acids, particularly alpha-linolenic acid (ALA), as well as polyphenols and antioxidants, which may help counteract oxidative stress and inflammation—both implicated in AD pathogenesis.

Several preclinical studies have shown that walnut-enriched diets improve cognitive function and decrease amyloid-beta aggregation in transgenic mouse models of Alzheimer's Disease. For example, a 2014 study published in the Journal of Alzheimer's Disease found that mice fed a walnut-enriched diet exhibited better learning skills, memory, and reduced anxiety compared to controls. Proposed mechanisms include reduction of oxidative damage, anti-inflammatory effects, and improved neuronal signaling.

Human studies are limited. Some observational data link higher nut consumption with improved cognitive performance in older adults, but these studies are not specific to walnuts or Alzheimer's Disease. There are currently few, if any, well-powered clinical trials directly testing walnuts as a treatment or preventive intervention for AD in humans.

In summary, while there is some scientific rationale and animal data supporting potential benefits of walnuts for Alzheimer's Disease, direct evidence in humans is lacking, and the overall strength of evidence is low (2/5).

More about Walnut (unspecified)
More about Alzheimer's Disease

Other ingredients used for Alzheimer's Disease

acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
Urolithin A
vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
mulberry
β-nicotinamide mononucleotide (NMN)
gastrodia
tinospora cordifolia
lingzhi
morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
algae
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid
7,8-Dihydroxyflavone
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Aronia melanocarpa
Anserine
Avocado
Agmatine
Acetylcholine
Amentoflavone
Acacetin
Alpha-Lipoic Acid
Astragaloside
Ampelopsin
Aniracetam
Apocynin
Black Seed
Bilobalide
Butylphthalide
Beta-hydroxybutyrate
Bacopin
Baicalein
Benfotiamine
Basidiomycota
Brahmi
Bacopa
Bifidobacteria
bacoside
Baicalin
Caffeic Acid
Centrophenoxine
Camellia sinensis
Caryophyllene
Cinnamomum
Crocin
Carnosine
Catalpol
Cyanidin
Curcuminoid
Curcumen
Chinese Ligustrum berry
Creatine
Curcuma
C-Phycocyanin
Convolvulus prostratus
Crocetin
Cytidine
Carnosic acid
Cannabigerol
Docosahexaenoic Acid
Decursin
Dihydrolipoic Acid
epicatechin
Ellagic Acid
Ergothioneine
Eicosapentaenoic Acid
Estrogen
Ecklonia
Flavonoids
Fo-Ti
Fish
Fatty acids
Flavanones
Flavans
Flavonones
Flavanols
Flavones
Gallic Acid
Ginsenosides
Garcinol
Ginkgetin
Galantamine
Gallate
Ginkgolides
Ginkgo Flavone Glycoside
Ginkgoside
Ginkgoheteroside
Glucoraphanin
Gastrodin
Ketone Salts
walnut

Products containing Walnut (unspecified)

We currently have no products on Caring Sunshine that contain this ingredient.