Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E, primarily in the form of alpha-tocopherol, has been investigated for its potential role in supporting or treating Alzheimer’s Disease (AD) due to its antioxidant properties. However, you mentioned "Alpha-Tocomonoenol," which is a less common variant; the vast majority of research is on alpha-tocopherol or tocotrienols. The rationale is that oxidative stress is implicated in the pathogenesis of AD, and Vitamin E may help counteract neuronal damage caused by free radicals. Several randomized controlled trials—most notably the 1997 Sano et al. study (NEJM, 1997)—have suggested that high-dose vitamin E (2000 IU/day) may modestly slow the progression of functional decline in patients with moderate AD. Later studies, such as the TEAM-AD VA Cooperative Randomized Trial (JAMA, 2014), found a similar modest benefit in delaying clinical progression, but did not show improvement in cognitive test scores. Importantly, high-dose vitamin E supplementation has raised safety concerns, particularly regarding increased risk of hemorrhagic stroke and all-cause mortality in some populations. There is currently no strong evidence supporting the use of "Alpha-Tocomonoenol" specifically for AD, and the benefit of vitamin E in general remains controversial. Clinical guidelines generally do not recommend vitamin E as standard therapy for AD, primarily due to inconsistent evidence and potential safety issues.

More about Vitamin E (Alpha-Tocomonoenol)
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Other ingredients used for Alzheimer's Disease

acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
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vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
mulberry
β-nicotinamide mononucleotide (NMN)
gastrodia
tinospora cordifolia
lingzhi
morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
algae
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soy isoflavones
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Ginkgo Flavone Glycoside
Ginkgoside
Ginkgoheteroside
Glucoraphanin
Gastrodin
Ketone Salts
walnut

Other health conditions supported by Vitamin E (Alpha-Tocomonoenol)

Alzheimer's Disease
Arteriosclerosis
Free Radical Damage
Hair (loss or thinning)
Hepatitis
Inflammation

Products containing Vitamin E (Alpha-Tocomonoenol)

We currently have no products on Caring Sunshine that contain this ingredient.