Evidence supporting the use of: Terpenoids
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Terpenoids, also known as isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from five-carbon isoprene units. There is scientific interest in the potential of certain terpenoids to support or treat Alzheimer's disease (AD), primarily based on preclinical and early clinical studies. Research has shown that some terpenoids, such as ginkgolides (from Ginkgo biloba), curcumin (from turmeric), and cannabinoids (from cannabis), possess neuroprotective, antioxidant, and anti-inflammatory properties, which may be beneficial in slowing the progression of neurodegenerative diseases like AD. Furthermore, animal and cell studies suggest that terpenoids can inhibit beta-amyloid aggregation and reduce neuroinflammation—two key pathological features of Alzheimer’s disease.

However, evidence from human clinical trials remains limited and inconclusive. For example, while Ginkgo biloba extract (rich in terpenoids) has been studied in several randomized controlled trials, results have been mixed, with some studies reporting modest cognitive benefits and others showing no significant effect. The mechanisms by which terpenoids might exert positive effects in AD are still under investigation, and their clinical efficacy has not been firmly established. Thus, while there is a scientific rationale and preclinical evidence to support ongoing research, current clinical evidence supporting the use of terpenoids in Alzheimer's disease is weak, justifying a relatively low evidence rating.

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acai berry
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akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
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chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
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quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
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selenium
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tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
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vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
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gastrodia
tinospora cordifolia
lingzhi
morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
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cocoa
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soy isoflavones
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7,8-Dihydroxyflavone
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Apocynin
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Bacopa
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bacoside
Baicalin
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Caryophyllene
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Curcuma
C-Phycocyanin
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Crocetin
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Docosahexaenoic Acid
Decursin
Dihydrolipoic Acid
epicatechin
Ellagic Acid
Ergothioneine
Eicosapentaenoic Acid
Estrogen
Ecklonia
Flavonoids
Fo-Ti
Fish
Fatty acids
Flavanones
Flavans
Flavonones
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Flavones
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Ginsenosides
Garcinol
Ginkgetin
Galantamine
Gallate
Ginkgolides
Ginkgo Flavone Glycoside
Ginkgoside
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Products containing Terpenoids

We currently have no products on Caring Sunshine that contain this ingredient.