Evidence supporting the use of: Monounsaturated fatty acid (unspecified)
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Monounsaturated fatty acids (MUFAs), such as those found in olive oil, have been investigated for their potential role in supporting brain health and reducing the risk of Alzheimer's Disease (AD). Scientific interest is based on epidemiological studies suggesting that diets rich in MUFAs, like the Mediterranean diet, are associated with lower incidence of cognitive decline and AD. The proposed mechanisms include anti-inflammatory effects, improvement of lipid profiles, and reduction of oxidative stress—factors implicated in the pathogenesis of AD.

However, the evidence specifically linking unspecified monounsaturated fatty acids to direct treatment or significant prevention of Alzheimer's Disease remains limited. Most of the data come from observational studies and dietary pattern research, rather than randomized controlled trials (RCTs) of isolated MUFA supplementation. Some RCTs on Mediterranean diet interventions report modest cognitive benefits, but it is unclear if MUFAs are primarily responsible, given the complex mix of nutrients in such diets. Reviews and meta-analyses generally conclude that while there may be a protective association, causality is unproven, and the efficacy of MUFAs as a standalone intervention for AD is not established.

In summary, there is scientific interest and some epidemiological evidence supporting a possible benefit, but the overall evidence is modest (rated 2/5), and there is no high-quality clinical trial data confirming MUFAs as an effective treatment or preventive for Alzheimer's Disease.

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algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
Bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
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caprylic acid
catechins
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chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaenoic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
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L-serine
L-theanine
Lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
magnesium
Marine lipid
Matcha
medium chain triglycerides (MCT)
Melatonin
N-acetyl-cysteine (NAC)
Naringin
Niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic compounds
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
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resveratrol
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hericium mushroom
hemp
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icariin
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Products containing Monounsaturated fatty acid (unspecified)

We currently have no products on Caring Sunshine that contain this ingredient.