Evidence supporting the use of: Siler root
For the health condition: Allergies (respiratory)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Siler root (Fang Feng, Saposhnikovia divaricata) is a traditional Chinese medicinal herb widely used in Eastern medicine, especially in formulas targeting respiratory allergies such as allergic rhinitis and hay fever. In Traditional Chinese Medicine (TCM), siler root is believed to "expel wind" and "dispel dampness," concepts that are often associated with symptoms of respiratory allergies, such as sneezing, nasal congestion, and runny nose. Historically, siler root has been a key component of classic formulas like "Yu Ping Feng San," which is used to boost immunity and prevent colds and allergic symptoms.

However, the scientific evidence supporting the use of siler root for respiratory allergies is limited. Some in vitro and animal studies suggest that siler root may have anti-inflammatory and immunomodulatory effects, which could theoretically help with allergic symptoms. For example, certain compounds isolated from siler root (such as chromones and coumarins) have demonstrated the ability to inhibit histamine release and reduce inflammatory markers in preliminary studies. Despite these findings, robust clinical trials in humans are lacking, and most of the evidence remains preclinical or anecdotal.

In summary, while siler root is traditionally used for respiratory allergies and there is some low-level scientific rationale, high-quality clinical evidence is insufficient. Its use is primarily justified by historical and traditional practice rather than strong scientific validation.

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