Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Probiotics have been investigated for their potential role in the prevention and management of respiratory allergies, such as allergic rhinitis and asthma. The rationale is based on the modulation of the gut microbiota and the subsequent influence on the immune system, particularly the balance between T-helper cell subtypes involved in allergic responses. Several randomized controlled trials and meta-analyses have examined the effects of various probiotic strains (notably Lactobacillus and Bifidobacterium species) in both children and adults with respiratory allergies.

The evidence is mixed and generally modest. Some studies report that probiotics may reduce the incidence or severity of allergic rhinitis symptoms, and a few show improvements in quality of life or decreases in medication use. However, other studies find no significant effect compared to placebo. Meta-analyses suggest potential, but results are inconsistent and depend heavily on the specific strains used, timing, and duration of supplementation. There is some evidence for benefit in the prevention of eczema in infants, but for respiratory allergies, the benefit is less clear. Overall, while there is scientific investigation and some supportive data, the overall strength of evidence remains low to moderate, and probiotics are not a standard or universally recommended therapy for respiratory allergies at this time.

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