Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus, a genus of probiotic bacteria commonly found in fermented foods and supplements, has been investigated for its potential to support or treat respiratory allergies, such as allergic rhinitis and asthma. The rationale stems from the ability of probiotics to modulate immune responses, particularly by influencing the balance between Th1 and Th2 immune pathways and regulating inflammatory cytokine production. Several randomized controlled trials and meta-analyses have examined various Lactobacillus strains (such as L. rhamnosus, L. casei, and L. paracasei) for their effect on allergic symptoms, with some studies reporting modest reductions in symptom severity, improved quality of life, or decreased medication use in patients with allergic rhinitis.

However, the evidence is inconsistent and often strain-specific. Some studies have found no significant benefit, and meta-analyses frequently note high heterogeneity and small effect sizes. The efficacy appears to depend on the specific Lactobacillus strain, dosage, duration, and population studied. Current clinical guidelines do not universally recommend probiotics for respiratory allergy management due to the limited and variable quality of the evidence. Nonetheless, the use of Lactobacillus for respiratory allergies is supported by a moderate amount of scientific research, though the overall strength of evidence remains low to moderate (rated 2/5), and more large-scale, high-quality trials are needed to draw firm conclusions.

More about Lactobacillus (unspecified)
More about Allergies (respiratory)

Other ingredients used for Allergies (respiratory)

Other health conditions supported by Lactobacillus (unspecified)

Products containing Lactobacillus (unspecified)