Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Black Seed (Nigella sativa) has a long history of traditional use for various ailments, including respiratory complaints. In recent years, scientific studies have investigated its effects on allergic conditions, particularly allergic rhinitis and asthma. Several randomized controlled trials and animal studies suggest that Black Seed and its active component, thymoquinone, may exert anti-inflammatory, antihistaminic, and immunomodulatory effects.

For example, a 2013 double-blind, placebo-controlled clinical trial published in Phytotherapy Research found that Nigella sativa oil supplementation significantly reduced symptoms of allergic rhinitis compared to placebo. Other studies have shown that thymoquinone can inhibit the release of histamine and modulate immune responses, potentially reducing airway inflammation and hyperreactivity.

However, while these findings are promising, most clinical trials are small and of short duration. There is a need for larger, high-quality studies to confirm efficacy and establish optimal dosing and safety profiles. As such, the use of Black Seed for respiratory allergies is supported by both traditional use and a growing body of preliminary scientific evidence, but it has not yet reached the level of strong, consensus-based clinical recommendation.

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