Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B12 (adenosylcobalamin) is supported by scientific evidence for use in individuals with alcoholism, primarily due to the high risk of B12 deficiency among chronic alcohol users. Alcoholism often leads to malnutrition and impaired absorption of several essential nutrients, including vitamin B12, due to damage to the gastrointestinal mucosa and poor dietary intake. Deficiency in B12 can cause neurological symptoms, anemia, and other systemic issues, which can complicate recovery and overall health in alcohol-dependent individuals.

Clinical guidelines and reviews highlight that screening for and correcting vitamin B12 deficiency is standard practice in the management of patients with alcohol use disorder, especially those with signs of neuropathy or macrocytic anemia. However, it is important to note that B12 supplementation is not a treatment for alcoholism itself but rather addresses the secondary complications of alcohol-induced malnutrition. The evidence supporting B12 administration is therefore moderate (rated as 3), as it is based on well-established pathophysiological mechanisms and clinical observations rather than direct studies showing that B12 supplementation treats or reduces alcohol dependence.

In summary, while vitamin B12 is not a cure for alcoholism, its supplementation is scientifically justified in affected patients with deficiency or at high risk, as part of a broader nutritional and medical support regimen.

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