Evidence supporting the use of: Vitamin E (mixed alpha-tocopherol)
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E, particularly in the form of mixed alpha-tocopherol, is often marketed and used as an antioxidant supplement for aging prevention. The scientific rationale stems from Vitamin E’s role as a lipid-soluble antioxidant, which can help protect cell membranes from oxidative damage caused by free radicals—a process implicated in aging and age-related diseases. Several observational studies have shown that higher dietary intake of Vitamin E is associated with a lower risk of age-related diseases, such as cardiovascular disease and cognitive decline. However, randomized controlled trials (RCTs) evaluating Vitamin E supplementation in healthy older adults have not consistently demonstrated a significant benefit in slowing aging or preventing age-related diseases. In some studies, high-dose Vitamin E supplementation has not reduced all-cause mortality or the incidence of major chronic diseases, and in rare cases, may even increase risk when taken in excess.

Overall, while there is a scientific rationale and some limited supportive evidence for the use of Vitamin E in aging prevention, robust clinical trial data are lacking and do not clearly support its efficacy for this purpose. The evidence is mixed, with most large-scale RCTs showing no clear benefit. As a result, the evidence rating for Vitamin E in aging prevention is 2 out of 5—indicating limited scientific support, primarily based on mechanistic and observational data rather than conclusive clinical outcomes.

More about Vitamin E (mixed alpha-tocopherol)
More about Aging (prevention)

Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
Fo-Ti
Fucoxanthin
fibroblast growth factor
Ginsenosides
Gac
Gerovital H3
Glabridin

Products containing Vitamin E (mixed alpha-tocopherol)

We currently have no products on Caring Sunshine that contain this ingredient.