Evidence supporting the use of: Vitamin C (sodium ascorbate)
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (including its sodium ascorbate form) has some scientific support for its role in the prevention of aging-related changes, although the evidence is modest and far from definitive. Vitamin C is a potent antioxidant, helping to neutralize free radicals, which are implicated in cellular aging and the development of age-related diseases. Several observational studies have linked higher vitamin C intake with reduced wrinkles, better skin appearance, and lower risk of some chronic diseases associated with aging, such as cardiovascular disease. Experimental studies in vitro and in animal models also demonstrate that vitamin C can support collagen synthesis, protect DNA from oxidative damage, and modulate inflammation—all processes relevant to aging. However, the direct evidence from randomized controlled trials (RCTs) in humans for vitamin C supplementation preventing or slowing general aging is limited. While topical vitamin C can improve some signs of skin aging, oral supplementation has not been conclusively shown to extend lifespan or broadly prevent age-related decline in humans. The majority of large-scale studies suggest that for individuals with adequate dietary intake, additional supplementation produces little extra benefit. Therefore, while there is a scientific rationale and some supportive evidence for vitamin C’s role in aging prevention, the strength of the evidence is moderate and not wholly convincing.

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