Evidence supporting the use of: Vitamin C (mixed ascorbates)
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid, including mixed ascorbates) is justified for aging (prevention) primarily on a scientific basis, although the evidence supporting its efficacy is moderate and not definitive. Vitamin C is a potent antioxidant, and oxidative stress is a well-documented contributor to the aging process and to age-related diseases. It plays an essential role in neutralizing free radicals, regenerating other antioxidants (such as vitamin E), and supporting collagen synthesis, which is important for skin integrity and wound healing. Epidemiological studies have observed that higher dietary intake of vitamin C is associated with healthier aging markers, such as reduced risk of cardiovascular disease, better skin health, and improved immune function. However, randomized controlled trials in humans have not consistently demonstrated that vitamin C supplementation slows aging or extends lifespan. Most studies suggest that supplementation is beneficial primarily in individuals with low baseline levels or deficiencies, rather than in the general, well-nourished population. There is also limited evidence that vitamin C may modestly improve skin appearance and reduce oxidative DNA damage, but these effects do not equate to a broad anti-aging benefit. Overall, while the biological rationale is strong and some data are supportive, the evidence is insufficient to recommend vitamin C supplementation solely for aging prevention in healthy adults.

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