Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Mixed carotenoids—such as beta-carotene, lutein, lycopene, and zeaxanthin—are natural pigments found in fruits and vegetables and are known for their antioxidant properties. The use of carotenoids in the context of aging prevention is supported by a moderate body of scientific evidence. Epidemiological studies have shown that higher dietary intake of carotenoid-rich foods is associated with reduced risks of age-related diseases, including certain cancers, cardiovascular diseases, and ocular disorders like age-related macular degeneration (AMD). Carotenoids are thought to contribute to aging prevention primarily through their ability to neutralize free radicals, thereby reducing oxidative stress, which is a major contributor to cellular aging and age-associated pathologies.

Randomized controlled trials have provided mixed results. Some studies demonstrate that supplementation with mixed carotenoids can improve skin health, enhance immune function, and protect against oxidative DNA damage. However, the evidence is less robust when it comes to direct prevention of aging or extension of lifespan in humans. Notably, excessive supplementation, particularly with single carotenoids like beta-carotene in smokers, has been linked to adverse effects.

In summary, while there is scientific rationale and some clinical evidence supporting the role of mixed carotenoids in mitigating factors commonly associated with aging, the overall strength of evidence for their use specifically as anti-aging agents is moderate. More large, well-controlled human studies are needed to establish definitive benefits for aging prevention.

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Nature's Sunshine Perfect Eyes