Curcuminoids, the active compounds in turmeric (Curcuma longa), have garnered significant scientific interest for their potential anti-aging effects. Research indicates that curcuminoids possess strong antioxidant and anti-inflammatory properties, which are key mechanisms implicated in the aging process. Several in vitro and animal studies have shown that curcumin can reduce oxidative stress, modulate signaling pathways related to cellular senescence, and protect against DNA damage—factors associated with aging and age-related diseases.

Human studies, although more limited, suggest that curcumin supplementation may improve markers of oxidative stress and inflammation in older adults. Some clinical trials have reported benefits such as improved endothelial function, decreased inflammatory cytokines, and better cognitive performance in elderly populations. However, most of these studies are of short duration, have small sample sizes, and often use bioavailability-enhanced formulations of curcumin due to its poor absorption.

While traditional uses of turmeric are mostly related to general health and inflammation rather than explicit "anti-aging" claims, the current scientific evidence provides a moderate basis (rated 3/5) for the role of curcuminoids as an adjunct in strategies aimed at healthy aging and prevention of age-related decline. Larger, long-term clinical trials are needed to confirm these effects and determine optimal dosing regimens.