Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Curcumin, the active polyphenolic compound found in turmeric (Curcuma longa), has garnered significant scientific interest for its potential role in aging prevention. Preclinical studies suggest that curcumin exhibits strong antioxidant, anti-inflammatory, and neuroprotective properties. These effects are relevant in the context of aging, as oxidative stress and chronic low-grade inflammation (“inflammaging”) are recognized contributors to cellular aging and age-related diseases. In animal models, curcumin has been shown to modulate signaling pathways involved in longevity, such as the sirtuin, AMPK, and mTOR pathways. It also appears to reduce markers of oxidative damage and improve cognitive and cardiovascular function in aged animals. Human evidence is growing, but remains limited and somewhat inconsistent. Some small-scale clinical trials have reported improvements in markers of oxidative stress, inflammation, and even cognitive function in older adults taking curcumin supplements. However, other studies have failed to find significant benefits, possibly due to issues with curcumin’s low bioavailability and differences in formulations used. Overall, while there is promising scientific evidence from laboratory and animal studies and some early human trials, more large-scale, long-term clinical research is needed to confirm curcumin’s efficacy in aging prevention. Thus, the use of curcumin for this purpose is justified by a moderate level of scientific evidence.

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Other ingredients used for Aging (prevention)

Other health conditions supported by curcumin

Products containing curcumin

Nature's Sunshine Turmeric Curcumin (Formerly CurcuminBP)