Evidence supporting the use of: Collagen
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Collagen supplementation has gained popularity as a means of supporting skin health and preventing visible signs of aging, such as wrinkles and decreased skin elasticity. Scientific evidence for the efficacy of oral collagen supplementation is steadily growing. Several randomized controlled trials have demonstrated that ingesting hydrolyzed collagen peptides can improve skin elasticity, hydration, and dermal collagen density in healthy adults, particularly women aged 35 and over. For example, a 2019 systematic review published in the Journal of Drugs in Dermatology found that daily oral collagen supplements for 8–12 weeks led to statistically significant improvements in skin elasticity and moisture compared to placebo. The proposed mechanism involves the absorption of collagen peptides, which may stimulate the body's own collagen production by activating fibroblasts in the dermis.

However, it should be noted that not all studies have found dramatic benefits, and most research so far is industry-sponsored with relatively small sample sizes. There is also debate about how much of the ingested collagen is absorbed intact and incorporated into skin tissue. While topical collagen is less well supported due to poor penetration, oral supplementation does have a plausible biological basis and a growing number of supportive clinical studies. Overall, while more independent, large-scale research is needed, current evidence moderately supports the use of collagen for aging prevention, particularly for improving skin appearance and hydration.

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