Evidence supporting the use of: Cistanche
For the health condition: Aging (prevention)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Cistanche is a traditional Chinese medicinal herb that has gained attention for its potential anti-aging properties. While its use in Traditional Chinese Medicine (TCM) for enhancing vitality and longevity is well documented, recent scientific studies have begun to explore its effects on aging-related processes. Preclinical research, primarily in animal models and cell cultures, suggests that Cistanche extracts may exert anti-aging effects through antioxidative, anti-inflammatory, and neuroprotective mechanisms. Some studies have demonstrated that Cistanche polysaccharides can increase the activity of antioxidant enzymes (such as SOD and catalase), reduce oxidative stress markers, and improve mitochondrial function—factors implicated in the aging process. Additionally, certain compounds in Cistanche, like echinacoside, may help protect neurons and enhance cognitive function in animal models of aging.
However, human clinical evidence remains limited. A few small-scale trials have investigated Cistanche for fatigue and cognitive support in elderly populations, but these studies are not robust enough to definitively confirm anti-aging benefits. Most claims remain extrapolated from animal or in vitro research, and larger, well-designed human trials are needed. In summary, while Cistanche’s use for aging prevention is rooted in tradition and supported by promising but preliminary scientific findings, the overall quality of evidence is modest (rated 2 out of 5), warranting cautious optimism pending further research.
Other ingredients used for Aging (prevention)
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid7-hydroxymatairesinol (HMR)
7-Keto-DHEA
8-Prenylnaringenin
Abalone
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
Algae
algal oil
Algal protein
Allantoin
Almond fruit
Alpha hydroxy acids
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
anemarrhena asphodeloides
anserine
anthocyanidins
anthocyanins
anthocyanosides
antler
Antrodia camphorata
apigenin
apple
apricot
argan nut oil
Aronia melanocarpa
ascorbyl palmitate
ashitaba
ashwagandha
astaxanthin
astragaloside
astragalus
avocado
beta-carotene
bioflavonoids
bird\'s nest
Brassica
Brussel sprouts
Carnosine
carotene (unspecified)
carrot
catalase
cauliflower
Chinese Ligustrum berry
cistanche
coenzyme Q10 (CoQ10)
collagen
cruciferous
cryptoxanthin
curcumin
Curcuminoid
cycloastragenol
DHEA
DHEA (dehydroepiandrosterone)
dismutase
dodder
Dunaliella
Dunaliella salina
ellagic acid
epicatechin
Epidermal Growth Factor
epigallocatechin gallate (EGCG)
ergothioneine
fibroblast growth factor
fisetin
flavonoids
flaxseed
fo-ti
fucoxanthin
Gac
Gerovital H3
ginkgo biloba
Ginsenosides
Glabridin
goji berry
green tea
greens blend (proprietary)
Haematococcus pluvialis
hazelnut
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
L-carnosine
lutein
Lycium
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oolong tea
Peptides
Phytoene
Phytofluene
polypeptide complex (proprietary)
polyphenols
protein
pyrroloquinoline quinone
quercetin
resveratrol
Rhodiola
royal jelly
Salidroside
selenium
Shilajit
silicon
soy isoflavones
soybean
Squalene
Trans-pterostilbene
Tremella
Triterpenes
turmeric
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
Watermelon
Xanthophyll
Yerba mate
Zinc
β-nicotinamide mononucleotide (NMN)
Other health conditions supported by cistanche
Aging (prevention)Alzheimer's Disease
Anemia
Appetite (deficient)
Athletic and Exercise Aids
Benign Prostate Hyperplasia
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Circulation (poor)
Convalescence
Depression
Diabetes
Energy (lack of)
Fatigue
Free Radical Damage
Hypertension
Kidney Stones
Memory and Brain Function
Muscle Tone (lack of)
Osteoporosis
Pain (general remedies for)
Premature Ejaculation
Prostatitis
Sex Drive (low)
Testosterone (low)
Wounds and Sores
Products containing cistanche
Nature's Sunshine Chinese TCM Negative Pack
Nature's Sunshine KB-C TCM Concentrate
