Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Beta-carotene is a precursor to vitamin A and is recognized for its antioxidant properties. The rationale behind its use for aging prevention is primarily based on its ability to neutralize free radicals, which are implicated in cellular aging and age-related diseases. Several observational studies have suggested that higher dietary intake of beta-carotene (mainly through fruits and vegetables) is associated with reduced risk of chronic diseases often linked with aging, such as cardiovascular disease and certain cancers. However, intervention trials using beta-carotene supplements have yielded mixed and sometimes negative results. For example, large randomized controlled trials like the ATBC and CARET studies found no benefit—and even potential harm (increased lung cancer risk in smokers)—from high-dose beta-carotene supplementation.

At present, there is limited direct evidence that beta-carotene supplementation slows the aging process or prevents age-related decline in healthy adults. The potential anti-aging effects likely come from a broader dietary pattern rich in antioxidants rather than from isolated supplementation. Therefore, while the biological plausibility exists, and some epidemiological studies are supportive, the clinical evidence for beta-carotene specifically as an anti-aging agent is weak. Most medical guidelines recommend obtaining beta-carotene from food sources rather than supplements, especially in populations at risk (e.g., smokers). Overall, the scientific support for beta-carotene in aging prevention is limited, and the evidence rating reflects this.

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