Evidence supporting the use of: Astaxanthin
For the health condition: Aging (prevention)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Astaxanthin is a naturally occurring carotenoid pigment found in microalgae, yeast, salmon, trout, krill, shrimp, and crayfish. Its use in supporting aging (prevention) is primarily justified by scientific evidence, though the level of evidence is moderate rather than strong. Several preclinical and human studies suggest astaxanthin’s potent antioxidant capacity helps combat oxidative stress, a major contributor to aging and age-related diseases. Astaxanthin is significantly more effective than other carotenoids (like beta-carotene or lutein) in scavenging free radicals and protecting cell membranes from lipid peroxidation.
Clinical trials in humans have reported that astaxanthin supplementation can improve skin elasticity, reduce the appearance of wrinkles, and decrease age spots, likely due to its ability to protect skin from UV-induced damage and inflammation. Some studies also indicate benefits in cognitive function, eye health, and cardiovascular parameters in older adults, all of which are relevant to healthy aging. However, most clinical studies are small, short-term, and sometimes industry-sponsored. Large-scale, long-term trials are lacking.
In summary, while astaxanthin’s antioxidant and anti-inflammatory properties are well-documented and there is moderate human evidence supporting its role in mitigating some signs of aging, the overall quality and quantity of clinical evidence do not yet warrant a higher rating. Continued research is needed to confirm its efficacy and establish optimal dosing for anti-aging purposes.
Other ingredients used for Aging (prevention)
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Ellagic Acid
Other health conditions supported by astaxanthin
Aging (prevention)Alzheimer's Disease
Arthritis
Athletic and Exercise Aids
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cataracts
Chemotherapy (reducing side effects)
Cholesterol (high)
Circulation (poor)
Cirrhosis of the Liver
Colitis
Convalescence
Dementia
Diabetes
Diabetic Retinopathy
Exercise
Fatigue
Fatty Liver Disease
Free Radical Damage
Glaucoma
Hypertension
Inflammation
Macular Degeneration
Memory and Brain Function
Muscle Tone (lack of)
Nerve Damage
Rheumatoid Arthritis
Skin Care (general)
Triglycerides (high)
Wrinkles