Evidence supporting the use of: Ashwagandha
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ashwagandha (Withania somnifera) has a long history of use in Ayurvedic medicine, where it is classified as a Rasayana—a rejuvenative herb believed to promote longevity, vitality, and resistance to aging. Traditional texts suggest ashwagandha helps maintain youthfulness, physical stamina, and cognitive clarity with advancing age. The roots and leaves have been used in various formulations to combat weakness, improve energy, and slow down age-related decline.

Modern scientific research on ashwagandha’s anti-aging effects is limited but growing. Some animal studies suggest that ashwagandha may possess antioxidant properties, reduce markers of cellular aging, and modulate stress hormones (such as cortisol), which are associated with accelerated aging. Small human studies have indicated potential benefits for stress reduction, improved sleep, and cognitive function, all of which may indirectly support healthy aging. However, direct evidence from large, well-controlled clinical trials specifically examining ashwagandha for aging prevention in humans is lacking.

In summary, ashwagandha’s use for aging prevention is rooted in traditional Ayurvedic practice, with preliminary scientific findings offering some support for its antioxidant and adaptogenic effects. Nonetheless, more robust clinical research is needed to confirm its efficacy for anti-aging purposes.

More about ashwagandha
More about Aging (prevention)

Other ingredients used for Aging (prevention)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
7-hydroxymatairesinol (HMR)
7-Keto-DHEA
8-Prenylnaringenin
Abalone
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
Algae
algal oil
Algal protein
Allantoin
Almond fruit
Alpha hydroxy acids
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
anemarrhena asphodeloides
anserine
anthocyanidins
anthocyanins
anthocyanosides
antler
Antrodia camphorata
apigenin
apple
apricot
argan nut oil
Aronia melanocarpa
ascorbyl palmitate
ashitaba
ashwagandha
astaxanthin
astragaloside
astragalus
avocado
beta-carotene
bioflavonoids
bird\'s nest
Brassica
Brussel sprouts
Carnosine
carotene (unspecified)
carrot
catalase
cauliflower
Chinese Ligustrum berry
cistanche
coenzyme Q10 (CoQ10)
collagen
cruciferous
cryptoxanthin
curcumin
Curcuminoid
cycloastragenol
DHEA
DHEA (dehydroepiandrosterone)
dismutase
dodder
Dunaliella
Dunaliella salina
ellagic acid
epicatechin
Epidermal Growth Factor
epigallocatechin gallate (EGCG)
ergothioneine
fibroblast growth factor
fisetin
flavonoids
flaxseed
fo-ti
fucoxanthin
Gac
Gerovital H3
ginkgo biloba
Ginsenosides
Glabridin
goji berry
green tea
greens blend (proprietary)
Haematococcus pluvialis
hazelnut
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
L-carnosine
lutein
Lycium
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oolong tea
Peptides
Phytoene
Phytofluene
polypeptide complex (proprietary)
polyphenols
protein
pyrroloquinoline quinone
quercetin
resveratrol
Rhodiola
royal jelly
Salidroside
selenium
Shilajit
silicon
soy isoflavones
soybean
Squalene
Trans-pterostilbene
Tremella
Triterpenes
turmeric
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
Watermelon
Xanthophyll
Yerba mate
Zinc
β-nicotinamide mononucleotide (NMN)

Other health conditions supported by ashwagandha

Addictions (drugs)
Addictions (general remedies for)
Afterbirth Pain
Aging (prevention)
Alcoholism
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Anger (excessive)
Angina
Anorexia
Anxiety
Anxiety Disorders
Appetite (deficient)
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autoimmune Disorders
Backache
Bedwetting
Body Building
Cancer (prevention)
Cancer Treatment (reducing side effects)
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Erectile Dysfunction
Exercise
Fatigue
Fear (excessive)
Fibromyalgia Syndrome
Goiter
Grief and Sadness
Hair (graying)
Hair (loss or thinning)
Hair Care (general)
Headache (general)
Headache (tension)
Heart (weakness)
Hot Flashes
Hypertension
Hypothyroid
Hysteria
Infertility
Inflammation
Insomnia
Irritability
Leucorrhea
Lyme Disease
Memory and Brain Function
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Miscarriage (prevention)
Mood Swings
Muscle Tone (lack of)
Nervous Exhaustion
Nervousness
Neurosis
Nightmares
Nocturnal Emission
Obsessive Compulsive Disorder
Pain (general remedies for)
Parkinson's Disease
Peripheral Neuropathy
Pets (supplements for)
PMS (general)
PMS Type C
PMS Type D
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Premature Ejaculation
Prolapsed Uterus
Sex Drive (low)
Sleep (restless and disturbed)
Stress
Syphilis
Tension
Testosterone (low)
Thinking (cloudy)
TMJ
Tremors
Triglycerides (high)
Tuberculosis
Vitiligo
Weight Gain
Weight Loss
Worry
Adrenal Fatigue
Cancer (natural therapy for)
Cholesterol (high)
Circulation (poor)
Concentration (poor)
Depression
Diabetes
Digestion (poor)
Migraine
Osteoporosis
Rheumatoid Arthritis
Wounds and Sores
Chronic Obstructive Pulmonary Disorder