Evidence supporting the use of: Amino acids
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Amino acids, the building blocks of proteins, have garnered scientific interest for their potential role in supporting healthy aging and possibly mitigating some age-related decline. As people age, muscle mass typically decreases—a phenomenon known as sarcopenia—which can lead to frailty and loss of independence. Essential amino acids, particularly branched-chain amino acids (BCAAs) like leucine, are critical for stimulating muscle protein synthesis. Several studies have shown that dietary supplementation with essential amino acids or high-quality protein can help older adults maintain or increase muscle mass and strength, especially when combined with resistance exercise.

Beyond musculoskeletal health, some research suggests amino acids may support immune function and metabolic health in aging populations. However, evidence for direct "anti-aging" effects—such as the prevention of age-related diseases or extension of lifespan—is less robust and more preliminary. Most of the benefits relate to maintaining physiological function rather than slowing intrinsic aging processes.

In summary, while there is scientific rationale and some supportive evidence for the use of amino acids to help counteract muscle loss and support general health in older adults, claims regarding prevention of aging itself are not strongly substantiated. The quality of evidence is moderate, with most studies focusing on sarcopenia rather than aging per se.

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7-hydroxymatairesinol (HMR)
7-Keto-DHEA
8-Prenylnaringenin
Abalone
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
Algae
algal oil
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Allantoin
Almond fruit
Alpha hydroxy acids
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
anemarrhena asphodeloides
anserine
anthocyanidins
anthocyanins
anthocyanosides
antler
Antrodia camphorata
apigenin
apple
apricot
argan nut oil
Aronia melanocarpa
ascorbyl palmitate
ashitaba
ashwagandha
astaxanthin
astragaloside
astragalus
avocado
beta-carotene
bioflavonoids
bird\'s nest
Brassica
Brussel sprouts
Carnosine
carotene (unspecified)
carrot
catalase
cauliflower
Chinese Ligustrum berry
cistanche
coenzyme Q10 (CoQ10)
collagen
cruciferous
cryptoxanthin
curcumin
Curcuminoid
cycloastragenol
DHEA
DHEA (dehydroepiandrosterone)
dismutase
dodder
Dunaliella
Dunaliella salina
ellagic acid
epicatechin
Epidermal Growth Factor
epigallocatechin gallate (EGCG)
ergothioneine
fibroblast growth factor
fisetin
flavonoids
flaxseed
fo-ti
fucoxanthin
Gac
Gerovital H3
ginkgo biloba
Ginsenosides
Glabridin
goji berry
green tea
greens blend (proprietary)
Haematococcus pluvialis
hazelnut
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
L-carnosine
lutein
Lycium
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oolong tea
Peptides
Phytoene
Phytofluene
polypeptide complex (proprietary)
polyphenols
protein
pyrroloquinoline quinone
quercetin
resveratrol
Rhodiola
royal jelly
Salidroside
selenium
Shilajit
silicon
soy isoflavones
soybean
Squalene
Trans-pterostilbene
Tremella
Triterpenes
turmeric
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
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Zinc
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