Evidence supporting the use of: Alpha-Linolenic Acid
For the health condition: Aging (prevention)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Alpha-Linolenic Acid (ALA) is an omega-3 fatty acid found in plant sources such as flaxseed, chia seeds, and walnuts. While ALA is essential for human health and has been studied for its potential benefits in cardiovascular health, its use for aging prevention is supported by limited scientific evidence. Research indicates that diets rich in omega-3 fatty acids may have beneficial effects on markers associated with aging, such as inflammation and oxidative stress. Some studies suggest that higher dietary intake of ALA is linked to reduced risk of age-related diseases, such as cardiovascular disease and cognitive decline. However, the evidence specifically supporting ALA in preventing or slowing the biological aging process is not robust.
Most clinical trials and observational studies focus on long-chain omega-3 fatty acids (EPA and DHA), primarily found in fish oil, which are more bioactive than ALA. When consumed, only a small fraction of ALA is converted to EPA and DHA in the body. There is some mechanistic rationale, as omega-3 fatty acids can modulate inflammation and cellular aging pathways, but direct, high-quality evidence for ALA's efficacy in aging prevention in humans is lacking. Therefore, while there is some preliminary scientific support, especially by association with healthy dietary patterns, the evidence is moderate at best and not conclusive.
More about Alpha-Linolenic Acid
More about Aging (prevention)
Other ingredients used for Aging (prevention)
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Ellagic Acid
Other health conditions supported by Alpha-Linolenic Acid
Aging (prevention)Alzheimer's Disease
Arteriosclerosis
Arthritis
Blood Clots (prevention of)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Depression
Diabetes
Eczema
Fat Metabolism (poor)
Fatty Liver Disease
Hypertension
Inflammation
Inflammatory Bowel Disorders
Lupus
Memory and Brain Function
Metabolic Syndrome
Migraine
Osteoporosis
Psoriasis
Rheumatoid Arthritis
Skin (dry and/or flaky)
Triglycerides (high)