Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin A and its derivatives (retinoids) are commonly used in dermatology for the treatment of various skin conditions, including age spots (also known as liver spots or solar lentigines). The scientific support for the use of Vitamin A in this context primarily comes from studies involving topical retinoids (such as tretinoin, a form of retinoic acid derived from Vitamin A). These compounds have been shown in multiple clinical trials to improve pigmentation irregularities and promote skin cell turnover, which can reduce the appearance of hyperpigmented lesions like age spots.

Topical tretinoin has demonstrated efficacy in lightening solar lentigines and improving overall skin tone by accelerating the rate of epidermal cell turnover and dispersing melanin granules. Several double-blind, placebo-controlled studies have confirmed the effectiveness of topical retinoids in reducing the pigmentation of age spots and photoaged skin. However, it should be noted that these effects are primarily documented for prescription-strength retinoids rather than over-the-counter retinyl esters or plain Vitamin A (retinol).

Oral supplementation with Vitamin A is not typically used for treating age spots, and there is limited evidence to support the efficacy of non-prescription, non-retinoic forms of Vitamin A for this indication. The evidence, therefore, is moderate and pertains mainly to topical pharmacologic derivatives of Vitamin A, rather than the nutrient itself.

More about Vitamin A (retinyl not specified)
More about Age Spots

Other ingredients used for Age Spots

Other health conditions supported by Vitamin A (retinyl not specified)

Products containing Vitamin A (retinyl not specified)