Evidence supporting the use of: Suma
For the body system: Adrenal Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Suma (Pfaffia paniculata), sometimes referred to as "Brazilian ginseng," has a long history of use in traditional South American herbal medicine. It has been used as a general tonic, adaptogen, and "energy booster," with folk practitioners claiming it helps the body adapt to stress, which implicates support for the adrenal glands. However, direct scientific studies investigating Suma’s effects on the adrenal glands specifically are very limited. Most evidence for its use in adrenal support is derived from traditional uses and extrapolation from studies on its adaptogenic properties.

Preclinical research suggests Suma contains saponins (notably pfaffosides), ecdysteroids, and other phytochemicals that may have adaptogenic effects, helping the body resist various stressors. Some small animal and in vitro studies have reported anti-inflammatory, immunomodulatory, and antioxidant effects, which could theoretically support adrenal function indirectly. However, these findings are not robustly validated in human clinical trials targeting adrenal health.

In summary, Suma’s use for adrenal support is primarily based on traditional herbal medicine practices, with limited scientific data available to substantiate its efficacy for this specific system. As such, while it is widely marketed as an “adrenal support” ingredient, evidence remains mostly anecdotal and historical rather than scientifically established.

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