Evidence supporting the use of: Gland (unspecified)
For the health condition: Adrenal Fatigue
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
The use of "Gland (unspecified)"—often referring to glandular extracts from animal sources such as adrenal, thyroid, or pituitary glands—to support or treat "Adrenal Fatigue" is primarily justified by tradition rather than scientific validation. Historically, glandular therapy has its roots in early 20th-century "organotherapy," where it was believed that consuming animal glands could support the function of corresponding human organs. Proponents of glandular supplements argue that they contain nutrients, enzymes, or hormones that might help restore adrenal function in states of fatigue or stress. However, "Adrenal Fatigue" itself is not a medically recognized diagnosis, and there is a lack of rigorous scientific evidence supporting both the condition and the efficacy of glandular extracts for its treatment. Most claims for these supplements are anecdotal or stem from naturopathic and integrative health traditions. There are no large, well-controlled clinical trials demonstrating benefit, and concerns exist regarding the safety and standardization of such supplements. Thus, while historically rooted in alternative medicine practices, the use of glandular extracts for "Adrenal Fatigue" is not supported by strong scientific evidence.