Evidence supporting the use of: Codonopsis
For the health condition: Adrenal Fatigue

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Codonopsis pilosula, commonly known as Dang Shen or "poor man's ginseng," has a long history of use in Traditional Chinese Medicine (TCM) as an adaptogen and a general tonic. In TCM, Codonopsis is used to tonify the "Qi" (vital energy), support the spleen and lungs, and combat fatigue and weakness. These traditional uses have led to its modern application as a possible remedy for so-called "adrenal fatigue," a non-medical term used to describe a collection of nonspecific symptoms such as tiredness, body aches, and sleep disturbances, purportedly due to chronic stress and "adrenal exhaustion." While Codonopsis is often included in herbal formulas marketed for adrenal support, there is little direct scientific evidence validating its effectiveness for this specific condition.

Some laboratory and animal studies suggest Codonopsis may have immunomodulatory, anti-fatigue, and adaptogenic properties, but these findings have not been robustly translated into clinical trials for "adrenal fatigue" (which itself is not recognized as a diagnosable medical condition by mainstream medicine). Thus, Codonopsis is primarily used for "adrenal fatigue" based on traditional herbal practice and extrapolation from its general tonic and adaptogenic effects, rather than on scientific validation specific to this indication.

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