Evidence supporting the use of: Herbal blend (proprietary)
For the body system: Adrenal Cortex

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Herbal blends labeled as "proprietary" for supporting the adrenal cortex are primarily justified by traditional rather than scientific evidence. Historically, herbal medicine systems such as Traditional Chinese Medicine (TCM), Ayurveda, and Western herbalism have used various herbs—such as ashwagandha, licorice root, rhodiola, schisandra, and holy basil—to help the body adapt to stress. These herbs are often grouped as "adaptogens," a category believed to help normalize physiological functions and support the body’s stress response, which involves the adrenal glands and, by extension, the adrenal cortex. The concept of using herbal blends for adrenal support is rooted in centuries of empirical use, with practitioners observing improved energy, resilience, and stress tolerance in patients. However, while some individual herbs in these blends have been studied (e.g., ashwagandha and rhodiola), there is minimal robust, high-quality scientific evidence supporting the effectiveness of proprietary multi-herb blends specifically for adrenal cortex health. Most studies are small, short-term, or lack rigorous controls, and the mechanisms affecting the adrenal cortex directly are not well established. Therefore, while the traditional use of herbal blends for adrenal support is well documented, scientific validation for such proprietary blends is limited, and evidence strength is modest at best.

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