Evidence supporting the use of: Genseng (not specified)
For the body system: Adrenal Cortex

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Ginseng, particularly Panax ginseng and Panax quinquefolius (American ginseng), has a long history of use in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Korean medicine. It is classified as an "adaptogen," a substance believed to help the body resist physical, chemical, or biological stressors. In these traditions, ginseng is used to support vital energy ("qi") and is often recommended for fatigue, weakness, and to promote overall vitality—attributes indirectly associated with adrenal health and stress resilience. While the adrenal cortex is not specifically mentioned in ancient texts, the traditional use of ginseng to bolster the body's response to stress aligns with modern understandings of adrenal cortex function (e.g., cortisol production). Modern scientific studies have investigated ginseng's adaptogenic effects, with some evidence suggesting it may influence the hypothalamic-pituitary-adrenal (HPA) axis and modulate stress responses in animals and humans. However, direct clinical evidence that ginseng specifically supports the adrenal cortex or improves conditions like adrenal fatigue is limited and inconsistent. Most studies focus on subjective measures of fatigue or stress rather than specific adrenal function. Thus, while traditional use is strong and some preliminary scientific data exist, rigorous validation for direct adrenal cortex support is lacking.

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