Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Fungi, particularly certain medicinal mushrooms like Reishi (Ganoderma lucidum), Cordyceps, and Rhodiola (although technically a plant, often grouped with adaptogens), have a long history of use in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Ayurveda for supporting overall vitality, resilience to stress, and energy levels—traits associated with adrenal function. In TCM, these fungi are considered adaptogens, substances believed to help the body adapt to stress and support homeostasis, which includes support of the adrenal cortex, the part of the adrenal gland involved in producing stress hormones like cortisol.

While there is a long-standing traditional basis for the use of certain fungi to support what is now understood as adrenal health, high-quality scientific studies directly linking fungal supplements to improved adrenal cortex function are limited. Some animal and in vitro studies suggest potential for certain mushrooms (e.g., Cordyceps) to modulate stress response and influence steroid hormone production, but robust human clinical evidence is lacking. Most claims are extrapolated from broader adaptogenic effects rather than specific adrenal cortex support.

Therefore, fungi are traditionally used for adrenal support, but current scientific validation specifically for adrenal cortex effects remains modest. The evidence rating of 2 reflects substantial traditional use, with only preliminary scientific support.

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