Evidence supporting the use of: Eleutherococcus gracilistylus
For the body system: Adrenal Cortex

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Eleutherococcus gracilistylus, a species closely related to Eleutherococcus senticosus (Siberian ginseng), has a traditional use in Chinese medicine for its purported adaptogenic effects. In traditional herbal practice, Eleutherococcus species are believed to support the body’s resilience to stress, indirectly benefitting the adrenal cortex, which is central to the stress response. However, the majority of clinical and pharmacological studies focus on E. senticosus, not E. gracilistylus specifically. Historical records and traditional texts often group these species together, attributing to them properties that help the body adapt to stressors, enhance energy, and support general vitality—functions sometimes associated with adrenal health. While some in vitro and animal studies indicate possible adaptogenic and anti-fatigue effects, there is a lack of direct, high-quality clinical research specifically on E. gracilistylus and its effect on adrenal cortex function. Therefore, the evidence supporting E. gracilistylus for adrenal support is primarily traditional, with a modest rating due to the absence of robust, specific scientific validation.

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