Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Umckaloabo (Pelargonium sidoides) is a traditional herbal remedy used primarily in southern African ethnomedicine. Historically, it has been employed to treat various infections, particularly those involving the respiratory tract. Its use for adenitis (inflammation of lymph nodes) is not well-documented in scientific literature, but there is ethnobotanical evidence suggesting its application for general infections and inflammatory conditions, which may include lymphadenitis as part of a broader infectious syndrome. The traditional use rests on the plant's perceived antimicrobial and immune-modulating properties. Modern research has focused mainly on its effects in acute bronchitis and other respiratory infections, with some clinical trials supporting its benefit in these contexts. However, direct scientific studies specifically investigating Umckaloabo in the treatment of adenitis are lacking. Thus, while traditional use for infection-related inflammation gives some justification for its application in adenitis, robust clinical or mechanistic evidence is absent. The overall evidence is therefore rated as low to moderate (2 out of 5), reflecting reliance on ethnomedicinal reports and indirect evidence from related conditions rather than direct clinical validation for adenitis itself.

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