Evidence supporting the use of: Hedyotis diffusa
For the health condition: Adenitis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Hedyotis diffusa, also known as Oldenlandia diffusa or "Bai Hua She She Cao," is used in traditional Chinese medicine (TCM) to treat various inflammatory conditions, including adenitis (inflammation of lymph nodes). The herb is believed in TCM theory to "clear heat" and "resolve toxicity," which are conceptual frameworks for treating swelling and infections like adenitis. Historically, Hedyotis diffusa has been included in polyherbal formulations for "toxic swelling," "scrofula," and lymphadenitis, with records in classical Chinese medical texts. However, most modern scientific research focuses on its anticancer and anti-inflammatory properties in vitro or in animal models, with limited direct clinical evidence for adenitis specifically. Some pharmacological studies suggest it has immunomodulatory and anti-inflammatory effects, which could potentially be relevant for adenitis, but well-controlled clinical trials in humans for this indication are lacking. Therefore, its use for adenitis is primarily justified by tradition, and the quality of supporting evidence is low to moderate (rated 2/5), reflecting traditional use and limited preclinical studies rather than robust clinical validation.

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