Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ardisia species, particularly Ardisia japonica and Ardisia crenata, are used in traditional medicine systems of East Asia, including Traditional Chinese Medicine (TCM), to treat inflammatory conditions such as adenitis (inflammation of the glands, especially lymph nodes). The leaves and roots of these plants are often included in herbal formulations intended to "clear heat" and "detoxify," which in TCM terminology refers to reducing inflammation and swelling. Historical references and pharmacopeias cite the use of Ardisia for conditions such as swollen lymph nodes, sore throat, and similar presentations.

However, while there are some laboratory studies indicating that extracts from Ardisia species have anti-inflammatory and immunomodulatory properties, these are not specific to adenitis, and clinical trials in humans are lacking. The rationale for use in adenitis is therefore primarily grounded in traditional practice, with limited preclinical data providing only weak support for its effectiveness in this specific condition. Overall, the evidence is largely anecdotal or based on historical use, with scientific validation remaining insufficient.

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