Evidence supporting the use of: Sterones (unspecified)
For the health condition: Addison's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Sterones (a misspelling or nonspecific term for "steroids") are scientifically validated as the cornerstone of treatment for Addison's Disease (primary adrenal insufficiency). Addison's Disease is characterized by the inadequate production of glucocorticoids (mainly cortisol) and often mineralocorticoids (mainly aldosterone) by the adrenal cortex. The underlying pathophysiology is well-understood, and the replacement of these hormones is essential for survival and symptom control.

Synthetic corticosteroids such as hydrocortisone, prednisone, or dexamethasone are routinely prescribed to replace deficient glucocorticoids. Fludrocortisone is used when mineralocorticoid replacement is also necessary. Multiple clinical guidelines, including those from the Endocrine Society, recommend lifelong steroid replacement therapy as the standard of care for Addison's Disease. The efficacy of these agents is well-documented in both clinical trials and decades of clinical experience, with marked improvements in patient morbidity and mortality.

Thus, the use of "steroids" (sterones) in Addison's Disease is strongly supported by scientific evidence, and these medications remain the only effective and validated treatment for correcting the hormonal deficiencies associated with the disorder.

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More about Addison's Disease

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