Delivery systems are scientifically validated and widely used to support the treatment of addictions, particularly tobacco smoking and chewing. The most common form is Nicotine Replacement Therapy (NRT), which includes delivery systems such as patches, gums, lozenges, nasal sprays, and inhalers. These systems provide controlled amounts of nicotine to the body without the harmful byproducts of tobacco combustion, such as tar and carbon monoxide. Numerous randomized controlled trials and meta-analyses have established that NRT significantly increases the likelihood of quitting smoking compared to placebo or no treatment. The World Health Organization (WHO), Centers for Disease Control and Prevention (CDC), and other public health agencies recommend NRT as a first-line treatment for tobacco use disorder. Additionally, delivery systems for medications like bupropion and varenicline, taken orally, are also evidence-based interventions for nicotine addiction. The effectiveness of these delivery systems is attributed to their ability to alleviate withdrawal symptoms and cravings, making cessation attempts more successful. Scientific evidence supporting these interventions is robust, with decades of research and clinical practice guidelines consistently endorsing their use.