Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Pepper, particularly black pepper (Piper nigrum) and long pepper (Piper longum), has been used in various traditional medicine systems, such as Ayurveda and traditional Chinese medicine, as a general remedy for a variety of ailments, including support during addiction withdrawal or as part of detoxification regimens. The rationale in these systems often centers on pepper’s purported ability to stimulate digestion, increase bioavailability of other herbs, and improve overall vitality, which are considered supportive during states of imbalance, including substance dependence or withdrawal. Additionally, black pepper’s active compound, piperine, has been investigated for its effects on neurotransmitters and mood, but direct scientific evidence for its use in treating addiction is lacking. Clinical trials specifically examining pepper or piperine for addiction support in humans are virtually nonexistent. Any supporting evidence is either anecdotal or based on traditional practice rather than rigorous scientific validation. Therefore, while pepper may play a supportive role in traditional remedies for addiction, there is only minimal evidence—primarily historical or theoretical—justifying its use for this purpose. High-quality clinical research is needed before pepper can be recommended as a treatment or adjunct for addiction.

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