Evidence supporting the use of: Milk thistle
For the health condition: Addictions (general remedies for)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Milk thistle (Silybum marianum) has a long history of traditional use, primarily for liver health and detoxification. Its role in supporting or treating addictions is mostly rooted in folk and traditional medicine, where it has been used as a general tonic to support the liver, an organ often affected by substance abuse (e.g., alcohol, drugs). The active compound, silymarin, is believed to possess antioxidant and anti-inflammatory properties that help protect liver cells from toxins and promote regeneration.
While there is some preliminary scientific evidence that milk thistle may support liver function in individuals with alcoholic liver disease or other forms of hepatic stress, direct evidence for its effectiveness in treating addiction itself—whether to alcohol, drugs, or other substances—is limited. Most studies focus on liver biomarkers rather than addiction behaviors or withdrawal symptoms. In traditional herbal medicine, improved liver health is thought to aid the body’s natural detoxification processes, which may indirectly support recovery from substance use, but this is not the same as treating addiction or its psychological components.
In summary, the use of milk thistle for addiction is primarily justified by traditional beliefs in its detoxification and liver-supporting capabilities rather than robust scientific validation for addiction treatment specifically. Evidence for its role in addiction is limited and indirect.
More about milk thistle
More about Addictions (general remedies for)
Other ingredients used for Addictions (general remedies for)
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
beta caryophyllene
chamomile
citrus oil
eleuthero
ginseng
kudzu
l-phenylalanine
lavender
licorice root
magnesium
melatonin
milk thistle
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phytocannabinoids
protein
rhizome
valerian root
vitamin C
water
shen-chu
sweet flag
St. John's Wort
herbal blend (proprietary)
Albizia
Calamus
D-phenylalanine
Devil's Club
Dopamine
Other health conditions supported by milk thistle
Abdominal PainAddictions (general remedies for)
Alcoholism
Cancer Treatment (reducing side effects)
Chemical Poisoning
Chemotherapy (reducing side effects)
Cirrhosis of the Liver
Environmental Pollution
Fat Metabolism (poor)
Fatty Liver Disease
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Hangover
Heavy Metal Poisoning
Hepatitis
Jaundice (adults)
Liver Detoxification
Poisoning (general)
Products containing milk thistle
Nature's Sunshine CleanStart Mild
Nature's Sunshine Detox Basics (Best used by 7/31/25)
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Enviro-Detox
Nature's Sunshine Heavy Metal Detox
Nature's Sunshine Hepatic System
Nature's Sunshine Milk Thistle Combination
Nature's Sunshine Milk Thistle (Time Release)
Nature's Sunshine Super Antioxidant