Evidence supporting the use of: Amino acids
For the health condition: Addictions (drugs)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Amino acids have been explored as adjunctive treatments in addiction recovery, primarily due to their roles as building blocks for neurotransmitters involved in mood regulation and reward pathways. Scientific interest centers on amino acids such as L-tyrosine, L-tryptophan, and L-glutamine, which are precursors to dopamine, serotonin, and GABA, respectively. Some small studies and clinical observations suggest that amino acid supplementation may help alleviate withdrawal symptoms, reduce cravings, and support mood stabilization during recovery from substances like alcohol, opioids, and stimulants.

However, the quality and quantity of clinical evidence are limited. Most available studies are small, lack rigorous controls, or are open-label. Systematic reviews and meta-analyses have not established clear, consistent benefits, and professional guidelines do not recommend amino acids as primary treatments for addiction. Instead, their use is sometimes considered as part of broader nutritional support, particularly in individuals with documented deficiencies.

Overall, while there is a plausible biological rationale and some preliminary scientific support, the evidence base is weak (rating 2/5). More large-scale, well-controlled trials are needed to determine whether amino acid supplementation provides significant and consistent benefit in the treatment of drug addictions.

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