Evidence supporting the use of: Urea
For the health condition: Acne

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Urea is a naturally occurring compound that is widely used in dermatology, primarily as a topical agent for its keratolytic (exfoliating) and humectant (moisturizing) properties. In the context of acne, urea's primary role is to help soften and break down hardened, thickened skin, facilitating the removal of dead skin cells that can contribute to clogged pores. Low to moderate concentrations of urea (typically 5-10%) are found in over-the-counter creams and lotions for general skin hydration, while higher concentrations (up to 40%) are used for conditions like hyperkeratosis. The scientific evidence supporting urea's efficacy specifically for acne is limited. Most clinical research and dermatological guidance focus on urea’s benefits for dry, rough, or scaly skin, such as that seen in eczema, psoriasis, or ichthyosis. Only a few small studies and anecdotal reports suggest potential benefits in acne by improving skin texture and possibly enhancing penetration of other topical treatments. Urea is not considered a first-line or core therapy for acne; standard treatments include topical retinoids, benzoyl peroxide, and antibiotics. In summary, while urea may have auxiliary benefits in acne-prone skin by maintaining skin hydration and gently exfoliating, scientific validation for its use as a primary or direct acne treatment remains modest. It is more often used as an adjunct to enhance skin barrier function or reduce irritation from other acne therapies.

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Products containing Urea

We currently have no products on Caring Sunshine that contain this ingredient.