Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Tea polyphenols, particularly epigallocatechin-3-gallate (EGCG) found in green tea, have been investigated for their therapeutic potential in acne management. Scientific studies suggest that tea polyphenols possess anti-inflammatory, antioxidant, and antimicrobial properties, which are relevant to the pathogenesis of acne. In vitro research has demonstrated that EGCG can inhibit the growth of Cutibacterium acnes (formerly Propionibacterium acnes), the bacteria implicated in acne development. Additionally, EGCG has been shown to reduce sebum production by modulating androgen activity and influencing key enzymes involved in lipid synthesis in sebaceous glands.

A number of small clinical trials and pilot studies have explored the topical application of green tea extracts or purified polyphenols in individuals with mild to moderate acne. Results generally indicate a modest reduction in inflammatory and non-inflammatory lesions, with good tolerability and minimal side effects. For example, a randomized controlled trial published in 2016 found that a 2% green tea lotion applied twice daily for six weeks led to significant improvement in acne severity compared to placebo.

Although the body of evidence is not yet robust—studies are limited in size and scope—the available data support a biological rationale and some clinical efficacy for tea polyphenols in acne treatment. Larger, well-controlled studies are needed to firmly establish their therapeutic role and optimal formulation.

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