Pansit-pansitan (Peperomia pellucida) is an herb commonly used in traditional Filipino medicine, primarily for its anti-inflammatory and diuretic properties. In folk practices, it has been applied topically or consumed as a decoction to help with various skin conditions, including acne, largely due to its perceived ability to reduce inflammation and promote skin healing. The traditional use is based on anecdotal evidence and long-standing community practices rather than rigorous scientific studies.

From a scientific standpoint, some laboratory studies have demonstrated that Peperomia pellucida contains phytochemicals such as flavonoids, alkaloids, and tannins, which possess general anti-inflammatory and antimicrobial activities. However, there is a lack of direct clinical evidence or robust research specifically evaluating its effectiveness for acne treatment in humans. No controlled trials or dermatological studies have confirmed its efficacy against Propionibacterium acnes (now known as Cutibacterium acnes), the bacteria implicated in acne.

In summary, pansit-pansitan is traditionally used in the Philippines as a remedy for acne and other skin problems, but scientific validation for this specific application is minimal. The evidence supporting its use for acne remains largely anecdotal and rooted in traditional use rather than established clinical research.