Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ilex asprella, commonly known as "Gang Mei Gen" in traditional Chinese medicine (TCM), has a long history of use for various ailments, primarily for its anti-inflammatory, detoxifying, and immune-supportive properties. In TCM, acne and other skin eruptions are often thought to result from "heat" or "toxins" in the body, and Ilex asprella is traditionally prescribed to "clear heat" and "remove toxins." While there is some in vitro evidence that extracts from Ilex asprella possess anti-inflammatory and antimicrobial activities, there are no clinical trials or robust pharmacological studies that specifically investigate its efficacy for treating acne vulgaris in humans. The use of Ilex asprella for acne is thus largely based on traditional practice and theoretical frameworks rather than on modern scientific validation. In summary, while Ilex asprella is traditionally used to support skin health and may be included in multi-herb formulas aimed at managing acne, evidence supporting its direct effectiveness for this condition is limited to historical and ethnomedical records rather than clinical science.

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